What does PKA mean?

PKA in AZ Dictionary

(a) Skillfully Generally; alias.
(a) Previously Referred To As; alias.

PKA in Community Dictionary

It represents Pi Kappa Alpha. They have been known as PIKE's for short.Their national slogan is "Males whom love guys to love them."They often gravitate towards becoming firemen and like to shower together. by Angla HonReport definition
PKA, an acronym for Previously generally, or Professionally called. by Solange SkeeterReport definition
a cult, situated in maple ridge. by CassieReport definition
Protein Kinase AG protein-coupled receptor kinases (GRKs) represent a course of proteins that classically phosphorylate agonist-activated G protein-coupled receptors, causing uncoupling associated with receptor from additional G protein activation. Recently, we've reported that the heterotrimeric G protein á-subunit, Gáq/11, can mediate insulin-stimulated glucose transport. GRK2 includes a regulator of G protein signaling (RGS) domain with specificity for Gáq/11. For that reason, we postulated that GRK2 could be an inhibitor of this insulin signaling cascade causing glucose transportation in 3T3-L1 adipocytes. Inside study, we display that microinjection of anti-GRK2 antibody or siRNA against GRK2 enhanced insulin-stimulated insulin-responsive sugar transporter 4 (GLUT4) translocation, while adenovirus-mediated overexpression of wild-type or kinase-deficient GRK2 inhibited insulin-stimulated GLUT4 translocation also 2-deoxyglucose uptake. Notably, a mutant GRK2 lacking the RGS domain was without effect. Taken together, these outcomes indicate that through its RGS domain endogenous GRK2 features as a bad regulator of insulin-stimulated glucose transport by interfering with Gáq/11 signaling to GLUT4 translocation. Also, inhibitors of GRK2 may cause improved insulin sensitivity. by BreannReport definition

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