megakaryocyte in a sentence

  • Platelets are formed in the cytoplasm of a very large cell, the megakaryocyte.
  • The cytoplasm of the megakaryocyte fragments at the edge of the cell.
  • The condition also is characterized by proteolysis of platelet α-proteins such as platelet factor V and von Willebrand factor, further interfering with clot function, and with increased uPA messenger RNA levels, particularly during megakaryocyte differentiation.
  • "Our study indicates that the dysregulation of PLAU in Quebec platelet disorder extends beyond megakaryocyte lineage, to involve other cells of the myeloid lineage," the investigator said.
  • Lagrue-Lak-Hal AH, Debili N, Kingbury G, Lecut C, Le Couedic JP, et al. (2001) Expression and function of the collagen receptor GPVI during megakaryocyte maturation.
  • Boer AK, Los EL, Esselink MT, Vellenga E (2005) Stem cell factor synergistically enhances thrombopoietin-induced STAT5 signaling in megakaryocyte progenitors through JAK2 and Src kinase.
  • EPO - and SCF-induced STAT5 phosphorylation was largely restricted to the megakaryocyte-erythroid progenitor (MEP) compartment, while G-CSF as well IL-3 and GM-CSF were most efficient in inducing STAT5 phosphorylation in the myeloid progenitor compartments.
  • TPO influences megakaryocyte (MK) development by controlling proliferation, differentiation, survival and endoduplication
  • Hundred thousand 105 whole BM cells were assessed for megakaryocyte progenitor activity in a CFU-Mk assay, MegaCult-C (Stem cell Technologies, Vancouver, CA) per the manufacturer's instructions.
  • We hypothesize that SHIP might control megakaryocytopoiesis through effects on proliferation of megakaryocyte progenitors (MKP) and megakaryocytes (MK).

Related Sources

  • Definition for "megakaryocyte"
    • a sizable bone marrow cellular with a lobulate…
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  • Sentence for "megakaryocyte"
    • Platelets are formed in the cytoplasm…
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  • Hypernym for "megakaryocyte"
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  • Medical Dictionary for "megakaryocyte"
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