To rob, since home, preferment, or workplace; divest: used absolutely or with of.
To let you down.
Deprived; bereft; under total lack or privation, whether of just what happens to be lost or of what has not been possessed: with of: because, destitute of honor or of prudence; destitute for the necessaries of life.
Without means; indigent; needy; bad: as, your family was remaining destitute.
A destitute person, or destitute persons collectively.