cephalosporin definition

  • noun:
    • Any of various broad-spectrum antibiotics, closely associated with the penicillins, that were originally produced from the fungus Cephalosporium acremonium.
    • any one of a class of natural and synthetic antibiotics developed from Cephalosporium fungi, having a cepham framework.
    • any one of a class of chemical compounds, a few of which have therapeutically of use anti-bacterial activity, whose construction contains a beta-lactam ring fused to a six-membered ring containing a sulfur and a nitrogen atom. Initial of the series, cephalosporin C, had been discovered by G. Brotzu in 1955 in tradition broth of a Cephalosporium species found from the shore of Sardinia. Various other cephalosporins have-been discovered to be generated by types of earth micro-organisms (actinomycetes). Numerous semisynthetic analogs are tested for anti-bacterial result, and many of these are finding use as important clinically of use antibacterial representatives, a number of which may be taken by mouth for treatment of bacterial infections. The cephalosporins are the second-class of beta-lactam antibiotic drug to-be found, 1st becoming the penicillins plus current courses becoming the thienamycins and sulfazecins. The cephamycins are a variant of cephalosporins with a methoxyl group on the beta-lactam ring, making them more resistant to penicillinases. On the list of cephalosporins which have been found clinically helpful are cephalexin, cephaloridine, and cephalothin.
    • one of the broad spectrum antibiotic drug substances acquired from fungi and linked to penicillin (trade brands Mefoxin); addition of side chains features created semisynthetic antibiotics with greater anti-bacterial task
    • any one of numerous broad-spectrum antibiotics, closely about the penicillins, that have been originally produced from the fungus Cephalosporium acremonium.
    • Any of a course of natural and synthetic antibiotics created from Cephalosporium fungi, having a cepham structure.
    • any of a course of substances, some of which may have therapeutically helpful antibacterial activity, whose structure contains a beta-lactam band fused to a six-membered band containing a sulfur and a nitrogen atom. The initial for the series, cephalosporin C, ended up being found by G. Brotzu in 1955 in the culture broth of a Cephalosporium species found off the shore of Sardinia. Various other cephalosporins have already been found is generated by species of earth bacteria (actinomycetes). Many semisynthetic analogs have now been tested for antibacterial effect, and several of these have found use as important clinically helpful anti-bacterial agents, a number of which can be taken by mouth for treatment of microbial infection. The cephalosporins will be the second class of beta-lactam antibiotic drug becoming discovered, 1st being the penicillins plus recent courses becoming the thienamycins and sulfazecins. The cephamycins are a variant of cephalosporins with a methoxyl team in the beta-lactam ring, making them much more resistant to penicillinases. On the list of cephalosporins that have been discovered clinically of use are cephalexin, cephaloridine, and cephalothin.
    • one of many broad spectrum antibiotic substances acquired from fungi and associated with penicillin (trade brands Mefoxin); inclusion of part stores has actually produced semisynthetic antibiotics with better anti-bacterial activity

Related Sources

  • Sentence for "cephalosporin"
    • Alternately maudlin and accusatory, the letter…
    • View More
  • Antonym for "cephalosporin"
  • Hyponym for "cephalosporin"
  • Hypernym for "cephalosporin"
  • Cross Reference for "cephalosporin"
  • Same Context for "cephalosporin"
113 votes

How would you define cephalosporin?

All the definitions on AZdictionary were written by people just like you. Now's your chance to add your own!