an old area of southwest Asia involving the Tigris and Euphrates streams in modern Iraq. Most likely settled before 5000 B.C., the region had been home of numerous early civilizations, including Sumer, Akkad, Babylonia, and Assyria. It declined in importance after Mongol invaders ruined its substantial irrigation system in A.D. 1258.
A region in Southwest Asia spanning from rivers Euphrates and Tigris this is the web site of 1 of the most extremely old civilizations in the history of man.
The Brit Mandate of Mesopotamia, a League of Nations mandate from 1920 to 1932 which was the predecessor towards the separate state of Iraq.