Fumagilin-B definition

  • Bicyclohexyl-ammonium fumagillin, whose trade name had been Fumadil-B (Abbot Labs) the good news is is apparently called Fumagillin-B, is a whitish dissolvable antibiotic drug powder discovered in 1952; some beekeepers combine this with sugar syrup and feed it to bees to control Nosema condition. Fumagillin is more dissolvable than Fumadil. Its use within beekeeping is outlawed within the eu because it is a suspected teratogen (triggers birth problems). Fumagillin can stop blood-vessel development by binding to an enzyme called methionine aminopeptidase. Targeted gene disruption of methionine aminopeptidase 2 leads to an embryonic gastrulation problem and endothelial cellular growth arrest. Its produced from the fungi that causes stonebrood, Aspergillus fumigatus. Formula: (2E,4E,6E,8E)-10-{[(3S,4S,5S,6R)- 5-methoxy-4-[2-methyl-3-(3-methylbut-2-enyl) oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl]oxy}- 10-oxo-deca-2,4,6,8-tetraenoic acid by Maxwell Report definition
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